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Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) is an active compound that inhibits toxoplasmic encephalitis, as well as protozoan and bacterial infections. It is intended for research use only.
Active compound for toxoplasmic encephalitis inhibition
Inhibits protozoan and bacterial infections
For research use only
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Larsucosterol (trimethylamine) is a cholesterol metabolite and a potent liver X receptor (LXR) antagonist. It acts as an endogenous regulator, decreasing lipogenesis and inhibiting cholesterol biosynthesis by reducing mRNA levels and blocking SREBP-1 activation.
Inhibits cholesterol biosynthesis by decreasing HMG-CoA reductase mRNA levels.
Inhibits HMG-CoA reductase expression via SREBP1 activation and expression in hepatocytes.
Increases cell proliferation and decreases apoptosis in macrophages.
Inhibits activation of liver oxysterol receptor LXRα in macrophages.
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BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA forming a key ligand-receptor pathway together with TNFSF13/APRIL These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity BAFF/TNFSF13B Trimer Protein Human (HEK293 His-Flag) is the recombinant human-derived BAFF/TNFSF13B protein expressed by HEK293 with N-His N-Flag labeled tag
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APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation regulate tumor cell growth and may participate in mononuclear/macrophage-mediated immune process[1] APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture[2] APRIL protein has been widely used in the study of lymphatic malignancies APRIL protein is a type II membrane protein with cytoplasmic domain hydrophobic transmembrane domain and extracellular domain APRIL/TNFSF13 Trimer Protein Cynomolgus (HEK293 His-Flag-Avi) is produced by HEK293 cells (K112-L250) with N-terminal His Avi and Flag tags
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Recombinant human APRIL/TNFSF13 trimer produced in HEK293 cells and supplied with a His-Flag tag; designed for in vitro receptor binding and functional studies related to B-cell biology and lymphatic malignancies.
Suitable for receptor binding assays and biochemical characterization.
Trimeric form mimics the native ligand assembly for functional studies.
HEK293 expression supports mammalian folding and glycosylation.
Affinity tags enable straightforward purification and detection.
Optimized for cell signaling and ligand-receptor interaction experiments.
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AITRL a type II transmembrane protein is a ligand for glucocorticoid-induced TNFR-related protein (GITR) When AITRL binds to GITR GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions GITR/AITRL interaction plays a role in the pathogenesis of tumor inflammation as well as autoimmune diseases[1] Besides AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1 ICAM-1)[2] AITRL/TNFSF18 Protein Human (Biotinylated HEK293 His-Flag) is a recombinant biotinylated human AITRL (Q72-S199) with N-terminal His and Flag tag which is expressed in HEK293
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